Recent advances: Gastroenterology

Recent Advances in Gastroenterology 11

The majority of chapters are timely (in 2007). It would be of interest, in the breast cancer chapter, on Page 68, if the author would give his views on the thoughts of some senior breast specialists, that breast cancer screening may be picking up tumours so small (with the associated stresses and workload) that they would be clinically irrelevant in that woman’s lifetime. This contrary view to ...

Recent Therapeutic Advances in Gastroenterology and Hepatology

The past year has seen major therapeutic advances in gastroenterology and hepatology. Two areas with notable gains are related to infectious diseases: novel treatments directed against recurrent Clostridium difficile infection (CDI) and against the hepatitis C virus (HCV). Clostridium difficile infection is an infectious colitis with high associated morbidity and mortality. Broad-spectrum antib...

Recent advances in pediatric gastroenterology, hepatology and nutrition

Pediatric gastroenterology, hepatology and nutrition are rapidly evolving, exciting and diverse disciplines. Because the field is so expansive, this commentary highlights important trends, rather than narrowly focusing on specific advances. Examples of advances in the highest impact and rapidly moving areas of pediatric gastroenterology are reviewed, including the intestinal microbiome, biomedi...

Recent Advances in Neonatal Gastroenterology and Neonatal Nutrition

Recent Advances in Hemophilia Gene Therapy

Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...